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spalt-dependent switching between two cell fates that are induced by the Drosophila EGF receptor
2001
Development
Signaling from the EGF receptor (EGFR) can trigger the differentiation of a wide variety of cell types in many animal species. We have explored the mechanisms that generate this diversity using the Drosophila peripheral nervous system. In this context, Spitz (SPI) ligand can induce two alternative cell fates from the dorsolateral ectoderm: chordotonal sensory organs and non-neural oenocytes. We show that the overall number of both cell types that are induced is controlled by the degree of EGFR
doi:10.1242/dev.128.5.723
fatcat:ysphx7livjbcriiqdwc6fuipca