Optimization of Pathogenetic Treatment of Secretory Diarrhea in Infants

O.K. Koloskova, L.A. Ivanova, N.N. Garas, U.I. Marusik
2014 Aktualʹnaâ Infektologiâ  
The aim of the research was to access clinical efficacy of oral rehydration therapy using III generation solutions in the treatment of secretory diarrhea in infants. To achieve this aim, on the basis of infectious box unit (enteric infections) of regional clinical hospital (Chernivtsi) we examined 116 infants, randomly selected, with acute gastroenteritis, who admitted to the hospital with signs of exycosis due to secretory diarrhea. Among examined patients, 73 (67.5 %) children with the
more » ... ren with the purpose of oral rehydration therapy received rehydration solutions, and 35 (32.4 %) patients received other rehydration solutions. Monitoring of the dynamics of patients' state enabled to state that, when we used III generation mixture as a main component of oral rehydration therapy, rate of positive dynamics in terms of clinical status of patients was significantly faster, in particular, body temperature, frequency and nature of bowel movements normalized significantly earlier, vomiting disappeared. In children treated with rehydration solutions, compared with patients receiving other rehydration solutions, odds ratio to confine only oral rehydration was 3.7 (95% CI 0.4–38.9) with an absolute risk to avoid the need for infusion therapy — 11 %.
doi:10.22141/2312-413x.1.02.2014.82186 doaj:0f02f5338a674498b84238462f63ca22 fatcat:jghcmrqmbjbcdkj5xencwrcn6u