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Simulated shift work in rats perturbs multiscale regulation of locomotor activity
2014
Journal of the Royal Society Interface
Motor activity possesses a multiscale regulation that is characterized by fractal activity fluctuations with similar structure across a wide range of timescales spanning minutes to hours. Fractal activity patterns are disturbed in animals after ablating the master circadian pacemaker (suprachiasmatic nucleus, SCN) and in humans with SCN dysfunction as occurs with aging and in dementia, suggesting the crucial role of the circadian system in the multiscale activity regulation. We hypothesized
doi:10.1098/rsif.2014.0318
pmid:24829282
pmcid:PMC4032547
fatcat:pb6axkgssjeyvjvnmjju3uhndu