Individual and Synergistic Anti-obesity Effect of Flax Seeds (Linum usitatissimum), Fenugreek Seeds (Trigonella foenum) and Black Seeds (Nigella sativa), in-vivo in Drosophila melanogaster

Adikeshavan Thilagavathy, Kavitha G Singh, Melantha Janet Lobo, Mayuri Mayuri
2021 International journal of pharmaceutical sciences review and research  
Obesity poses a major threat to global health, challenging the prevention of chronic diseases and health across the world. As synthetic medicines have their side effects, lately, there has been an inclination towards herbal remedies. The present study was conducted to evaluate the individual and syngeristic effect of Linum usitatissimum (flax seeds), Trigonella foenum graecum (fenugreek seeds) and Nigella sativa (black seeds) on obesity. In-vivo studies were performed in Drosophila as many
more » ... es and organs related to obesity and its associated disorders are analogous in Drosophila and humans. Obesity was induced by supplementing lipid and high concentration of glucose in the media. The effect of the seeds on obesity was studied by quantitative estimation of lipid content and carbohydrate content in the larvae grown in different media preparations and also by assessment of physical activity of the flies. The study revealed the efficient ability of the seeds to reduce obesity, synergistically as well as individually proving it to be a potential strategy to combat the obesity naturally.
doi:10.47583/ijpsrr.2021.v70i02.021 fatcat:x7wvbt5znjg3lhaxinkw7suzwy