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Pathogenesis of nitrofen-induced congenital diaphragmatic hernia in fetal rats
Journal of applied physiology
of nitrofen-induced congenital diaphragmatic hernia in fetal rats. J. Appl. Physiol. 83(2): 338-347, 1997.-Congenital diaphragmatic hernia (CDH) is a developmental anomaly characterized by the malformation of the diaphragm and impaired lung development. In the present study, we tested several hypotheses regarding the pathogenesis of CDH, including those suggesting that the primary defect is due to abnormal 1) lung development, 2) phrenic nerve formation, 3) developmental processes underlyingdoi:10.1152/jappl.1922.214.171.1248 pmid:9262424 fatcat:mdtrey7qnbdlhn3u4zfstak6xe