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The networked structure of contacts shapes the spreading of epidemic processes. Recent advances on network theory have improved our understanding of the epidemic processes at large scale. The relevance of several considerations still needs to be evaluated in the study of epidemic spreading. One of them is that of accounting for the influence of origin and destination patterns in the flow of the carriers of an epidemic. Here we compute origin-destination patterns compatible with empirical datadoi:10.1038/s41598-019-38722-4 pmid:30783178 pmcid:PMC6381217 fatcat:yqv4hlsq6vhl3kdpdz6p5i4yam