Quantitative Low-Dose Computed Tomography of the Lung Parenchyma and Airways for the Differentiation between Chronic Obstructive Pulmonary Disease and Asthma Patients

Huai Chen, Qing-si Zeng, Min Zhang, Rong-chang Chen, Ting-ting Xia, Wei Wang, Xiaoyin Xu, Yubao Guan
2017 Respiration  
ume, expiratory mean lung density (MLD), and expiratory EI -950 (%) and EI -850 (%). The COPD group had a significantly higher EI -950 (%) than the asthma group ( p = 0.008). There were significant differences among the three groups in lumen area (LA), wall area (WA), total area, and Pi10WA. The asthma group had significantly higher WA%/WV% than both the COPD ( p = 0.002) and the control group ( p = 0.012). There was high sensitivity in EI -950 (%), EI -850 (%) and expiratory MLD in the
more » ... ma and high sensitivity in LA and Pi10WA in small airways in the differential diagnosis of COPD and asthma. Conclusion: To aid the diagnosis, CT can provide quantitative measurements to differentiate between COPD and asthma patients.
doi:10.1159/000478531 pmid:28738344 fatcat:2lfft4ch3jhotcuvaprb2oy7bi