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Biased selection of leading process branches mediates chemotaxis during tangential neuronal migration
Current models of chemotaxis during neuronal migration and axon guidance propose that directional sensing relies on growth cone dynamics. According to this view, migrating neurons and growing axons are guided to their correct targets by steering the growth cone in response to attractive and repulsive cues. Here, we have performed a detailed analysis of the dynamic behavior of individual neurons migrating tangentially in telencephalic slices using high-resolution time-lapse videomicroscopy. Wedoi:10.1242/dev.025502 pmid:19060332 fatcat:5juz6lpntbe7pcdd4p3bgym4ie