Coexistence of pulmonary nocardiosis and aspergillosis in a patient of Chronic Obstructive Pulmonary Disease (COPD) is a diagnostic rarity. They pose a diagnostic challenge due to their indolent course masquerading as malignancy. Both Aspergillus and Nocardia infections are more likely to be present in patients who are immune compromised, have structural lung diseases, especially COPD or a history of surgery or trauma. They carry a high mortality despite timely identification and management.

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... e, we report one such rare association of Nocardia and Aspergillus in an immunocompetent patient of COPD.