Vitamin A and immunity to viral, bacterial and protozoan infections

R. D. Semba
1999 Proceedings of the Nutrition Society  
fax +1 410 955 0629, email Studies in animal models and cell lines show that vitamin A and related retinoids play a major role in immunity, including expression of mucins and keratins, lymphopoiesis, apoptosis, cytokine expression, production of antibody, and the function of neutrophils, natural killer cells, monocytes or macrophages, T lymphocytes and B lymphocytes. Recent clinical trials suggest that vitamin A supplementation reduces morbidity and mortality in different
more » ... ious diseases, such as measles, diarrhoeal disease, measles-related pneumonia, human immunodeficiency virus infection and malaria. Immune responses vary considerably during different infections, and the available data suggest that the modulation of immune function by vitamin A may also vary widely, depending on the type of infection and immune responses involved. https://doi.
doi:10.1017/s0029665199000944 fatcat:ea2uinyo4jfdhay5szhv6kqv6i