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Prediction and simulation of motion in pairs of transmembrane -helices
2007
Bioinformatics
Motivation: Motion in transmembrane (TM) proteins plays an essential role in a variety of biological phenomena. Thus, developing an automated method for predicting and simulating motion in this class of proteins should result in an increased level of understanding of crucial physiological mechanisms. We have developed an algorithm for predicting and simulating motion in TM proteins of the a-helix bundle type. Our method employs probabilistic motion-planning techniques to suggest possible
doi:10.1093/bioinformatics/btl325
pmid:17237094
fatcat:5r7zmdlswfc4vb74p7oxmgbeoa