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Cytokine mRNA expression profiles in rats infected with the intestinal nematode Nippostrongylus brasiliensis
Infection and Immunity
Although the immune responses to intestinal nematode infection have been well studied and have been shown to be strongly driven by Th2-associated cytokines in mice, such information has been limited with respect to rats. We investigated changes in levels of the mRNAs encoding interleukin-2 (IL-2), IL-3, IL-4, IL-5, IL-10, and gamma interferon in the mesenteric lymph nodes of rats infected with Nippostrongylus brasiliensis by reverse transcription-PCR in comparison with immunoglobulin Edoi:10.1128/iai.63.12.4653-4660.1995 fatcat:gy6hmmp42jgfjn4vkuozuds3bm