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This study investigates the physiological properties of parabrachial internal lateral (PBil) neurons that project to the paracentral thalamic (PC) nucleus using antidromic activation and single-unit recording techniques in anesthetized rat. We reported here that most of these neurons responded exclusively to the nociceptive stimulation of large receptive fields with a sustained firing that often outlasted the stimulus up to several minutes. These responses were depressed by intravenousdoi:10.1523/jneurosci.21-06-02159.2001 pmid:11245700 fatcat:z3hogtzvrncnrj35xtp6kqec2q