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Multiple functions and essential roles of nuclear receptor coactivators of bHLH-PAS family
Classical non-peptide hormones, such as steroids, retinoids, thyroid hormones, vitamin D3 and their derivatives including prostaglandins, benzoates, oxysterols, and bile acids, are collectively designated as small lipophilic ligands, acting via binding to the nuclear receptors (NRs). The NRs form a large superfamily of transcription factors that participate virtually in every key biological process. They control various aspects of animal development, fertility, gametogenesis, and numerousdoi:10.1515/enr-2016-0019 pmid:27560800 fatcat:7527nxbp2fbrtlf4vebihqs7ye