Networks for Joint Affine and Non-parametric Image Registration [article]

Zhengyang Shen, Xu Han, Zhenlin Xu, Marc Niethammer
2019 arXiv   pre-print
We introduce an end-to-end deep-learning framework for 3D medical image registration. In contrast to existing approaches, our framework combines two registration methods: an affine registration and a vector momentum-parameterized stationary velocity field (vSVF) model. Specifically, it consists of three stages. In the first stage, a multi-step affine network predicts affine transform parameters. In the second stage, we use a Unet-like network to generate a momentum, from which a velocity field
more » ... an be computed via smoothing. Finally, in the third stage, we employ a self-iterable map-based vSVF component to provide a non-parametric refinement based on the current estimate of the transformation map. Once the model is trained, a registration is completed in one forward pass. To evaluate the performance, we conducted longitudinal and cross-subject experiments on 3D magnetic resonance images (MRI) of the knee of the Osteoarthritis Initiative (OAI) dataset. Results show that our framework achieves comparable performance to state-of-the-art medical image registration approaches, but it is much faster, with a better control of transformation regularity including the ability to produce approximately symmetric transformations, and combining affine and non-parametric registration.
arXiv:1903.08811v1 fatcat:k7ilwbmhpvcelezw6yyu6bchha