Clinical efficacy of intravesical electrical stimulation on detrusor underactivity

Han Deng, Limin Liao, Juan Wu, Guoqing Chen, Xing Li, Zhaoxia Wang, Li Wan
2017 Medicine  
The aim of this study was to retrospectively evaluate the effectiveness of intravesical electrical stimulation (IVES) on detrusor underactivity (DU). From 2009 to 2016, a total of 105 patients with symptoms of DU who were treated with IVES were included in this retrospective study. The medical records, physical examination findings, urine culture results, and video-urodynamic studies were reviewed. Changes in post-void residual urine (PVR) and voiding efficiency (VE) were included for
more » ... of efficacy. Patients achieving a >50% reduction in the PVR were regarded as responders. A >80% reduction in the PVR was considered obvious improvement. A questionnaire was administered to patients with bladder sensation. Of the 105 patients, the information of residual urine volume and voiding volume was obtained in 89 patients, and detailed pre-and post-IVES bladder sensation information was available on 96 patients. Of the 89 patients, 47.2% (42/89) were responders and achieved a >50% reduction in the PVR. Obvious improvement in the PVR, defined as a >80% reduction, occurred in 27% (24/89) of the patients. VE developed in 76.4% (68/89) of the patients, and 30.3% (27/89) of the patients increased >50%. Significant improvements in the PVR and VE were observed during IVES treatment (P < .05). Based on the questionnaire, bladder sensation developed and was sustained in 44.8% (43/96) of the patients. IVES provides a promising method for improving the PVR and VE in a majority of patients with DU. Thus, IVES is worth to further study and carry out. Abbreviations: AIS = American Impairment Scale, ASIA = American Spinal Injury Association, CIC = clean intermittent catheterization, DU = detrusor underactivity, IVES = intravesical electrical stimulation, PVR = post-void residual urine, SCI = spinal cord injury, UTI = urinary tract infection, VE = voiding efficiency.
doi:10.1097/md.0000000000008020 pmid:28930838 pmcid:PMC5617705 fatcat:azy4oob7i5avjoki6aznucvnfq