The aim of this study was to develop spherical Hydroxy apatite with big diameter and porus. This material is expected to be biomatelials and protein absorbtion materials.Therefore we consider Crystal growth of few μm spherical porus hydroxy apatite (sHAp) formed with small tabular particles by simulated body fluid method in simulated body fluid We have experimented with adding sHAp1 as a seed crystal to a simulated body fluid of metastable region composition to apatite and growing it to several

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... tens of microns or more. . When a slightly sHAp1 was added to the simulated body fluid in the metastable region, nucleation was hardly generated and the particles grew large to about 100 times, and dome-like particles were obtained. Supply amount of Ca and P to each particle increased and the particle diameter increased by decreased amount of seed crystals adding. The seed crystal growed by clystal grows tinden then supply amount of ca and p other way not spherical and dome like. Ca and P were supplied anisotropically,due to The seed crystals that grew larger by crystal growth precipitated.As the result,The seed crystal grow into dome-like shape instead of spherical shape. Hydroxy apatite particles can be grow large by the seed crystal adding into the simulated body fluid.