Transposable Elements in Antirrhinum Majus

C. MARTIN, R. CARPENTER, T. ROBBINS, A. HUDSON, J. ALMEIDA, J. BARTLETT, S. MACKAY, E. COEN
1987 Journal of Cell Science  
The transposable element, Tam 3, gives rise to large-scale chromosomal rearrangements at a low frequency, when it is inserted at the nivea locus of Antirrhinum majus. Some deletions that result from imprecise excision of Tam 3 provide an allelic series for functional analysis of the nivea gene promoter. Rearrangements involving deletion, dispersion and inverted duplication of flanking sequences, where Tam 3 remains in situ, have also been identified. These rearrangements have been mapped at the
more » ... been mapped at the molecular level, and the behaviour of Tam 3 following rearrangement has been observed. It is clear that Tam 3 has enormous potential to restructure chromosomes through successive rounds of large-scale rearrangements.
doi:10.1242/jcs.1987.supplement_7.8 fatcat:7lg7qn4gcffpzozgksp24cryza