Photodynamic therapy on ocular neovascularization
眼内新生血管に対する光化学治療

Akira Obana, Yuko Gohto, Tokuhiko Miki, Susumu Nakajima, Isao Sakata, Takeshi Takemura, Toru Hirano
1995 Nippon Laser Igakkaishi  
The efficacy of photodynamic therapy using porphymer sodium (PF) and newly-developed chlorin derivative (ATX-S10) for occlusion of corneal new vessels has been evaluated experimentally. Twenty-six albino rabbits were treated with an intravenous injection of 2mg/kg of PF, followed by argon green laser (514nm) irradiation to the corneal new vessels with three varieties of energy at 24,48,72 and 96 hours after the injection, respectively. In another group of 4 rabbits, diode laser (672nm) was
more » ... iated with the energy from 43J/cm2 to 323J/cm2 at 4 and 6 hours after the administration of 12mg/kg of ATX-S10, respectively. The closure of corneal new vesseles was confirmed by slit-
doi:10.2530/jslsm1980.16.supplement_187 fatcat:yuwmfk25urex7gorhu2dzaxova