Associated factors with the prescription of potentially inappropriate medication for older adult in a public hospital

Priscilla M. SOUZA, Rafaela L. SANTOS, Monique G. CERQUEIRA, Gildomar L. VALASQUES-JUNIOR, Tuany S. SOUZA
2021 Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde  
Objective: To evaluate the factors associated with the prescription of potentially inappropriate medications for the older adult (PIM) in a public hospital. Methods: A prospective cross-sectional study was carried out, whose data were collected from the medical records of older adult patients, admitted to the medical clinic of a public hospital, by a trained researcher, not a member of the staff. The collection took place between November 2018 and January 2019. The medical records of patients
more » ... ed over 60 years, who were using at least one allopathic in-hospital medication, with a minimum of 48 hours of hospitalization, were included. Illegible prescriptions, or those containing only herbal medicines and / or vitamin supplements, were excluded. The PIMs were classified according to the Beers Criteria, 2019 update. Descriptive analysis of the data was performed using frequencies, means and standard deviation and bivariate analysis using the Chi-square and Fisher's Exact tests, with a level of significance. p <0.05, using the software and SPSS® v.21.0. Results: 42 medical records of the older adult were analyzed, where a 100% prevalence of use of PIM and polypharmacy was identified. The number of PIMs per patient was significantly associated with females (p = 0.020), with a higher prevalence of older adult women who used between 1 and 4 PIMs (64.1%); diagnosis (p = 0.006), with a higher prevalence of older adult people with circulatory tract diseases (54.5% using 1-4 PIM), endocrine, nutritional and metabolic diseases (85.7% using 1-4 PIM) ) and diseases of the circulatory system (83.5% in use ≥5 PIM); polypharmacy (p = 0.002) with higher prevalence of older adult people who used ≥10 medications (52%, in use ≥ 5 PIM). The main therapeutic classes of PIM were of the alimentary tract and metabolism (46%) and nervous system (22%). Conclusion: It is concluded that the prescription of PIM was very high, where all the older adult in this study were exposed, being significantly associated with the female gender, polyphar [...]
doi:10.30968/rbfhss.2021.122.0586 doaj:24a5184eac2e477988177572c3c4b7d7 fatcat:j32ays2vt5emljko6q2ig7h6zu