Clinical Course of Younger Patients With Central Retinal Vein Occlusion

Franco M. Recchia
2004 Archives of Ophthalmology  
To describe the clinical course of patients 55 years and younger with central retinal vein occlusion (CRVO). Design and Methods: Retrospective, noncomparative case series. Medical records of 67 patients were reviewed for demographic, photographic, clinical, and visual acuity (VA) data. Data from 57 patients with at least 6 months of follow-up (mean, 29.2 months) were analyzed statistically. Main Outcome Measures: Best-corrected visual acuity and incidence of intraocular neovascularization.
more » ... ts: Of 67 consecutive patients (55% men; mean age, 45 years), the median presenting VA was 20/50. Fortyfive patients (67%) were found to have at least 1 systemic disease. In 57 patients with at least 6 months of followup, the final VA was 20/40 or better in 42%, 20/50 to 20/ 100 in 18%, and 20/200 or worse in 40%. Visual decline was most common within 3 to 6 months of CRVO onset. Visual improvement was uncommon after 12 months. Of the 22 patients with a presenting VA of 20/40 or better, 36% declined to 20/400 or worse at the most recent examination. Of the 10 patients with a presenting VA of 20/ 200 to 20/400, 8 improved to 20/60 or better. None of the 6 patients with a presenting VA of counting fingers or worse improved. Intraocular neovascularization was diagnosed at 1 to 9 months following CRVO in 10 patients (18%). Neovascularization of the anterior segment developed in 6 patients (11%), including neovascular glaucoma in 3 (5%). The occurrence of neovascularization appeared to be unrelated to sex, age, presence of associated disease, duration of symptoms, or presenting VA.
doi:10.1001/archopht.122.3.317 pmid:15006842 fatcat:ae37372alvbijjcs5cxdmvg77i