Candida in saliva of Brazilian hemophilic patients

Claudio Maranhão Pereira, Fábio Ramôa Pires, Maria Elvira Pizzigatti Corrêa, Osvaldo di Hipólito Júnior, Oslei Paes de Almeida
2004 Journal of Applied Oral Science  
Hemophilia is a common hereditary hemorrhagic disorder, however little is known about the oral microflora of hemophilic patients. The aim of this study was to quantify the Candida and identify its species in non-stimulated saliva of hemophilic patients, and consider its relationship with clinical factors influencing Candida carriage. This study comprised evaluation of 86 hemophilic patients of the Hematology Center/UNICAMP and 43 healthy subjects as controls. All patients were submitted to
more » ... e submitted to anamnesis, intraoral examination and unstimulated saliva collection. Candida counts and species identification were performed in salivary samples. Candida was present in 64% of the hemophilic patients and in 44% of the healthy controls. C. albicans represented 65% and 68% of the isolated species, in hemophiliacs and control group respectively, and C. tropicalis was the second most common species in both groups. These results indicate that hemophilic patients carry Candida more frequently and in higher counts than healthy controls, independently of oral clinical parameter considered, as viral infections, complete dentures, transfusions of hemoderivatives, and salivary flow.
doi:10.1590/s1678-77572004000400009 pmid:20976401 fatcat:utkoe7nvmfbytelzx2hsxvoigy