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Purpose. To evaluate the possibility of application of electron microscopic analysis of human lacrimal fluid (LF) in the development of methods for early diagnosis and prognosis of ophthalmic diseases.Material and methods. Specimens of the reflex LF were collected from the lower conjunctival arch of eyes in 20 patients with a diagnosis of diabetic retinopathy, hyperopia, glaucoma, cataract and macular degeneration, and pelleted by centrifugation. The liquid portion of LF was examined by thedoaj:057173e866114c79b011dbeccb4edcc0 fatcat:ueccg2vzt5gyvn3clhp5dmhdqy