Early postexercise muscle glycogen recovery is enhanced with a carbohydrate-protein supplement

John L. Ivy, Harold W. Goforth, Bruce M. Damon, Thomas R. McCauley, Edward C. Parsons, Thomas B. Price
2002 Journal of applied physiology  
Early postexercise muscle glycogen recovery is enhanced with a carbohydrate-protein supplement. present study, we tested the hypothesis that a carbohydrate-protein (CHO-Pro) supplement would be more effective in the replenishment of muscle glycogen after exercise compared with a carbohydrate supplement of equal carbohydrate content (LCHO) or caloric equivalency (HCHO). After 2.5 Ϯ 0.1 h of intense cycling to deplete the muscle glycogen stores, subjects (n ϭ 7) received, using a rank-ordered
more » ... a rank-ordered design, a CHO-Pro (80 g CHO, 28 g Pro, 6 g fat), LCHO (80 g CHO, 6 g fat), or HCHO (108 g CHO, 6 g fat) supplement immediately after exercise (10 min) and 2 h postexercise. Before exercise and during 4 h of recovery, muscle glycogen of the vastus lateralis was determined periodically by nuclear magnetic resonance spectroscopy. Exercise significantly reduced the muscle glycogen stores (final concentrations: 40.9 Ϯ 5.9 mmol/l CHO-Pro, 41.9 Ϯ 5.7 mmol/l HCHO, 40.7 Ϯ 5.0 mmol/l LCHO). After 240 min of recovery, muscle glycogen was significantly greater for the CHO-Pro treatment (88.8 Ϯ 4.4 mmol/l) when compared with the LCHO (70.0 Ϯ 4.0 mmol/l; P ϭ 0.004) and HCHO (75.5 Ϯ 2.8 mmol/l; P ϭ 0.013) treatments. Glycogen storage did not differ significantly between the LCHO and HCHO treatments. There were no significant differences in the plasma insulin responses among treatments, although plasma glucose was significantly lower during the CHO-Pro treatment. These results suggest that a CHO-Pro supplement is more effective for the rapid replenishment of muscle glycogen after exercise than a CHO supplement of equal CHO or caloric content. catecholamines; glucose; lactate; insulin; nuclear magnetic resonance spectroscopy MUSCLE GLYCOGEN IS an essential fuel source for moderate-to high-intensity exercise. Once depleted, the capacity to perform at these exercise intensities is lost or severely limited (1, 2, 9, 11) . Therefore, the faster the muscle glycogen stores can be replenished after exercise the faster the recovery process and theoretically
doi:10.1152/japplphysiol.00394.2002 pmid:12235033 fatcat:knrzli5fzjertlmi52jtjatdvu