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Background: Behcet's disease (BD) is a chronic, inflammatory multisystemic condition of unknown etiology. Although the cause of BD is not clear, it is believed to be the result of an autoimmune process triggered by an infectious or environmental agent (possibly local to a geographic region) in a genetically predisposed individual. Objective: To detail current knowledge of the role of microorganisms in the pathogenesis of BD and review the infectious etiology of this disease. Methods: The reviewdoi:10.5372/1905-7415.0802.274 fatcat:yls476amirg63h6xt6i4i3uwji