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Temporally unpredictable stimuli influence murine and human behaviour, as previously demonstrated for sequences of simple sounds with regular or irregular onset. It is unknown whether this influence is mediated by an evaluation of the unpredictable sound sequences themselves, or by an interaction with task context. Here, we find that humans evaluate unrelated neutral pictures as more negative when these are presented together with a temporally unpredictable sound sequence, compared to adoi:10.1371/journal.pone.0131065 pmid:26098105 pmcid:PMC4476782 fatcat:gfar2ou3ybf4fbrusy3h3eofsa