Architectonic Mapping of the Human Brain beyond Brodmann

Katrin Amunts, Karl Zilles
2015 Neuron  
Brodmann has pioneered structural brain mapping. He considered functional and pathological criteria for defining cortical areas in addition to cytoarchitecture. Starting from this idea of structural-functional relationships at the level of cortical areas, we will argue that the cortical architecture is more heterogeneous than Brodmann's map suggests. A triple-scale concept is proposed that includes repetitive modular-like structures and micro-and meso-maps. Criteria for defining a cortical area
more » ... will be discussed, considering novel preparations, imaging and optical methods, 2D and 3D quantitative architectonics, as well as high-performance computing including analyses of big data. These new approaches contribute to an understanding of the brain on multiple levels and challenge the traditional, mosaic-like segregation of the cerebral cortex. Neuron 88, December 16, 2015 ª2015 Elsevier Inc. 1087 Neuron Primer
doi:10.1016/j.neuron.2015.12.001 pmid:26687219 fatcat:cyjyuzlk6jcn5c2hbqm5idhxb4