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The present investigation was carried out to find out the relationship between annual cycle of reproduction and thyroid activity in Melanochelys trijuga. The animals were studied in the annual seasonal cycle of reproduction which is distinguished into three separate periods namely regenerative, reproductive and recrudescent. Thyroid is an unpaired, oval shaped gland. Paraffin embedded thyroid sections were studied by bromophenol blue method for thyroglobulin. Liver sections were localized forfatcat:vygaxgzxczgenkpsn6yz3nasf4