A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
Growth Differentiation Factor 11 Promotes Survival of Mouse Retinal Ganglion Cells in Vitro through Smad2/3 Activation
Growth differentiation factor 11 (GDF11) was recently identified as a rejuvenation factor that promoted neurogenesis in aged mice. Previous work has revealed that gdf11 mRNA is expressed in the developing retina, and GDF11 protein can signal retinal ganglion cells (RGCs) to grow dendrites in vitro. The developmental expression pattern of GDF11 in RGCs and the impact of GDF11 on mammalian RGCs remain unknown. The current study investigated 1) the developmental time course of GDF11 expression indoi:10.22215/etd/2017-12051 fatcat:mk7ogqycijdolaol557jtclkga