Clinical and CT Findings of Adenovirus Pneumonia in Immunocompetent Adults, a Two-center Retrospectively Observation [post]

2020 unpublished
Adenovirus pneumonia account for 5%-10% of respiratory tract infections in children. However, it is rarely observed in immunocompetent patients. We sought to describe clinical and CT characteristics of community-acquired Adenovirus pneumonia in immunocompetent adults. Methods: 20 patients with clinically diagnosed adenovirus pneumonia from two hospitals were retrospectively included from January 2018 to December 2019. Medical records and chest CT of all patients were reviewed and summarized.
more » ... ults: A total of 20 patients who were consisted of 18 men and 2 women with a median age of 36 years-old (range, 18-48). The clinical findings of patients with adenovirus pneumonia is high fever (>39 o C) with the normal white blood cell (WBC) count and decreased Lymphocyte and elevated C-reactive protein. 10 cases complicated with mycoplasma infection when admission. Staphylococcus epidermidis was found in blood culture of 2 patients. CT findings included consolidation in all patients, ground glass opacity (GGO) in 13 patients, and pleural effusion in 12 patients. 13 patients were mechanically ventilated and 2 patients died during hospitalization. Conclusions: The most frequent finding of adenovirus pneumonia on CT was consolidation in the early stage. In adult patients with high fever, normal WBC count and decreased Lymphocyte, consolidation with/without GGO in the early stage may be a clue for suspecting adenovirus pneumonia. Background Adenovirus is a double-stranded DNA virus widely distributed in nature. It is mainly transmitted through the respiratory tract, causing not only upper respiratory tract infections but also pneumonia [1] . Adenovirus pneumonia is more common in children
doi:10.21203/ fatcat:3sron5o565hhxgkcvedfjinila