Remote memory access (RMA) is an emerging highperformance programming model that uses RDMA hardware directly. Yet, accessing remote memories cannot invoke activities at the target which complicates implementation and limits performance of data-centric algorithms. We propose Active Access (AA), a mechanism that integrates well-known active messaging (AM) semantics with RMA to enable high-performance distributed data-centric computations. AA supports a new programming model where the user

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... s handlers that are triggered when incoming puts and gets reference designated addresses. AA is based on a set of extensions to the Input/Output Memory Management Unit (IOMMU), a unit that provides high-performance hardware support for remapping I/O accesses to memory. We illustrate that AA outperforms existing AM and RMA designs, accelerates various codes such as distributed hashtables or logging schemes, and enables new protocols such as incremental checkpointing for RMA. We also discuss how extended IOMMUs can support a virtualized global address space in a distributed system that offers features known from on-node memory virtualization. We expect that AA and other IOMMU features can enhance the design of HPC operating and runtime systems in large computing centers. • We discuss how the IOMMU could enable hardware-based virtualization of remote memories.