The irritable bowel syndrome (SII) is characterized by alterations of intestinal motility and visceral sensibility, without organic cause. Is associated a psychiatric alterations and somatic symptoms in 80%, the anxiety or depression precede or is concomitants with gastrointestinal symptoms. To determine association between depression or anxiety on the basis of DSM-IV criteria and Scale of Hamilton in patients with criteria of Rome II. A total one hundred patients were randomized in two groups:

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... Hamilton for anxiety (n = 50) and DSM-IV for depression (n = 50), is correlated bi-variables (Pearson) in a descriptive and transversal study. The female gender represented 76% (n = 76), the relation F/ M; 4:1, the age average 49.7 years (R 18-89). Group DSM-IV in 62% (n = 31) had depression and 54% (n = 27) were women. The group Hamilton in 58% (n = 29) presented anxiety and 50% were women (n = 25). The correlation of Pearson (P < 0.1) for the female with anxiety was of P < 0.05 and in depression of P < 0.01, using an IC 95%. The manifestation of anxiety or depression appears in more of 50%, affects in greater proportion the female, reason why antidepressing therapy must be contemplated in the handling of the SII.