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Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns
2019
Nature Communications
Epigenetic processes, including DNA methylation (DNAm), are among the mechanisms allowing integration of genetic and environmental factors to shape cellular function. While many studies have investigated either environmental or genetic contributions to DNAm, few have assessed their integrated effects. Here we examine the relative contributions of prenatal environmental factors and genotype on DNA methylation in neonatal blood at variably methylated regions (VMRs) in 4 independent cohorts
doi:10.1038/s41467-019-10461-0
pmid:31186427
pmcid:PMC6559955
fatcat:hrrz4q6tafhghkxm4naltkxilm