A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is
The emergence of longer information-carrying and functional nucleotide polymers from random short strands was a major stepping stone at the dawn of life. But the formation of those polymers under temperature oscillation required some form of selection. A plausible mechanism is template-based ligation where theoretical work already suggested a reduction in information entropy. Here, we show how nontrivial sequence patterns emerge in a system of random 12mer DNA sequences subject to enzyme-baseddoi:10.1101/2020.08.18.253963 fatcat:zb7zqaydxnhj5c524qmigzjl7y