Neonatal sepsis is the most common problem encountered in all neonatal intensive care unit. It is a significant cause of morbidity and mortality in developing countries like India. Therefore neonatal sepsis needs early and accurate diagnosis and management with appropriate antibiotics for better outcome among NICU graduates This study was aimed to analyze the clinical profile , bacterial isolates in culture positive neonates and bacteriological sensitivity pattern of microbial organisms

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... and Method: All culture positive neonatal cases admitted in our NICU KKGMCH from January 2018 -December 2018 were analyzed retrospectively Study Design: Retrospective Descriptive study Results: Total of 90 cultures positive neonatal cases were analyzed. Among them about 35 neonates were preterm which constitutes about 36 %. Microbial organism most common in our nicu is klebsiella which constitutes around 39% and staphylococcus about 31%, coagulase negative staphylocoicci constitutes 9%, pseudomonas 9%. Klebsiella is sensitive to cefotaxime, piperacillin and tazobactum and ciprofloxacin, staphylococcus organism is sensitive to clindamycin and linezolid pseudomonas sensitive to cefaperazone sulbactum and piperacillin.