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Simulation Model of Trabecular Bone Remodeling Considering Effects of Osteocyte Apoptosis and Targeted Remodeling
2010
Journal of Biomechanical Science and Engineering
Bone structure is renewed or restructured in part by a load-dependent remodeling. In this study, a mathematical model of bone surface remodeling over a wide range of strain was established. We assumed that in a low strain range, bone resorption occurs at an accelerated rate with strain decrease owing to low strain-induced osteocyte apoptosis, and that in a high strain range, bone formation occurs at an accelerated rate with strain increase (targeted remodeling). In a physiological strain range,
doi:10.1299/jbse.5.539
fatcat:434iycwdnbdozhqqcmer3kl5gu