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Acid adaptation sensitizes Salmonella typhimurium to hypochlorous acid
1997
Applied and Environmental Microbiology
Acid adaptation of Salmonella typhimurium at a pH of 5.0 to 5.8 for one to two cell doublings resulted in marked sensitization of the pathogen to halogen-based sanitizers including chlorine (hypochlorous acid) and iodine. Acid-adapted S. typhimurium was more resistant to an anionic acid sanitizer than was its nonadapted counterpart. A nonselective plating medium of tryptose phosphate agar plus 1% pyruvate was used throughout the study to help recover chemically stressed cells. Mechanisms of
doi:10.1128/aem.63.2.461-467.1997
fatcat:4x6kmfjn3ncrthybssq4sefm2q