RNA Polymerase II Phosphorylated on CTD Serine 5 Interacts with the Spliceosome during Co-transcriptional Splicing

Takayuki Nojima, Kenny Rebelo, Tomás Gomes, Ana Rita Grosso, Nicholas J. Proudfoot, Maria Carmo-Fonseca
2018 Molecular Cell  
Highlights d S5P CTD Pol II associates with the catalytic spliceosome d Elongating Pol II complexes protect about 60 newly synthesized nucleotides d Co-transcriptional splicing associated with dominant 5 0 ss intermediate d U12-dependent introns are sequentially spliced in association with Pol II
doi:10.1016/j.molcel.2018.09.004 fatcat:lkmksou5ofbtfh4ex4mx6kuijm