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Expression and regulation of ClC-5 chloride channels: effects of antisense and oxidants
2001
American Journal of Physiology - Cell Physiology
Expression and regulation of ClC-5 chloride channels: effects of antisense and oxidants. Am J Physiol Cell Physiol 280: C1511-C1520, 2001.-Genetic mutations of the Cl Ϫ channel ClC-5 cause Dent's disease in humans. We recently cloned an amphibian ortholog of Xenopus ClC-5 (xClC-5) from the A6 cell line. We now compare the properties and regulation of ClC-5 currents expressed in mammalian (COS-7) cells and Xenopus oocytes. Whole cell currents in COS-7 cells transfected with xClC-5 cDNA had
doi:10.1152/ajpcell.2001.280.6.c1511
pmid:11350746
fatcat:y6jumoxkmbbtlkuz7a6s26kdv4