Alpha mating type-specific expression of mutations leading to constitutive agglutinability in Saccharomyces cerevisiae

S Doi, M Yoshimura
1985 Journal of Bacteriology  
Two mutants of Saccharomyces cerevisiae have been isolated and characterized. The mutants were constitutively agglutinable at 360C, the temperature at which wild-type cells agglutinate only after induction by mating pheromone. The mutant cells had other properties specific for the normal a cell type, i.e., conjugation with a cells, response to a mating pheromone, and production of a mating pheromone. The two mutations, cagi and cag2, were recessive and expressed only in a cells. cagl is liiked
more » ... ery closely to the MAT locus, but cag2 is unlinked to the MAT locus. These cag mutations complemented ste3-1. These results indicate that CAG genes are novel a-specific genes involved in the regulation of sex agglutinin synthesis.
doi:10.1128/jb.161.2.596-601.1985 fatcat:puc4ze4rmbh5vlthjnta3reu64