HIV Surveillance in a Large, Community-Based Study: Results from the Pilot Study of Project Accept (HIV Prevention Trials Network 043)

Estelle Piwowar-Manning, Agnes Fiamma, Oliver Laeyendecker, Michal Kulich, Deborah Donnell, Greg Szekeres, Laura Robins-Morris, Caroline E Mullis,, Ana Vallari, John Hackett, Timothy D Mastro, Glenda Gray (+7 others)
2011 BMC Infectious Diseases  
Project Accept is a community randomized, controlled trial to evaluate the efficacy of community mobilization, mobile testing, same-day results, and post-test support for the prevention of HIV infection in Thailand, Tanzania, Zimbabwe, and South Africa. We evaluated the accuracy of in-country HIV rapid testing and determined HIV prevalence in the Project Accept pilot study. Methods: Two HIV rapid tests were performed in parallel in local laboratories. If the first two rapid tests were
more » ... ests were discordant (one reactive, one non-reactive), a third HIV rapid test or enzyme immunoassay was performed. Samples were designated HIV NEG if the first two tests were non-reactive, HIV DISC if the first two tests were discordant, and HIV POS if the first two tests were reactive. Samples were re-analyzed in the United States using a panel of laboratory tests.
doi:10.1186/1471-2334-11-251 pmid:21943026 pmcid:PMC3198953 fatcat:gibbowgjindzrdvkkoodrljjhy