A COMPARATIVE STUDY OF CERVIX CYTOLOGY SMEARS WITH HISTOPATHOLOGICAL FINDINGS
Journal of Evolution of Medical and Dental Sciences
BACKGROUND Cervical cancer is the one of the most common cancer in the females. There is wide variation in the incidence of cervical cancer across the world. A decrease in the incidence and mortality of cervical cancer can be achieved with effective cervical cytology screening programme. The accuracy of the cervical cytology reporting, using The Bethesda system (TBS 2001) was determined by correlating the cervical cytology findings with the histopathological diagnosis, which is the gold
... is the gold standard one. MATERIALS AND METHODS This comparative study was carried out in our pathology department for three years between 1.1.2013 to 30.12.2015. All the Pap smears sent from the gynaecology department and from the health centres in Theni district were received in our pathology department. Our pathologists followed the Bethesda system 2001 for reporting the Pap smears. Those cases with abnormal findings such as atypical squamous cells and atypical glandular cells were included in this study. In the followup study, either cervix biopsy or the hysterectomy specimens with above said diagnosis were received in our department for histopathological examination. The Pap smear reports were correlated with the histopathological diagnosis. RESULTS Total number of Pap smears received in our department from the department of gynaecology was 3438. Among these, 2834 number of cases were excluded. The remaining 604 cases, 131 cases were LSIL, 286 cases were diagnosed as HSIL, 166 cases were squamous cell carcinoma. 9 cases were reported as ASCUS, 5 cases as AGUS and 7 cases were diagnosed as adenocarcinoma. Majority cases of Pap smears are in the 41-50 years of age group. The number of Pap smears received show increased incidence in the para 2 individuals. In our study, the highest incidence of Pap smear report was LSIL and it occurred in <30 years of age group. HSIL and SCC were observed in > 40 years of age group. 100% accuracy in cytology reporting and histopathology correlation was achieved. CONCLUSION Cervix cytology screening programme is the best method of early detection and prevention of cervical cancer for a mass population. Pap smear interpretation by TBS 2001 gives better communication and understanding to the gynaecologist. The accuracy of the cervical cytology reports according to The Bethesda system 2001 can be evaluated by the histopathological diagnosis which is the gold standard one. KEYWORDS Cervical Cytology, Pap Smears, Histopathology. HOW TO CITE THIS ARTICLE: Suryamoorthy D, Duraisamy K, Ramakrishnan R. A comparative study of cervix cytology smears with histopathological findings. BACKGROUND Cervical cancer is the second most common cancer in the females. There is wide variation in the incidence of cervical cancer across the world. 1,2 A decrease in the incidence and mortality of cervical cancer can be achieved with effective cervical cytology screening programme. The purpose of the Papanicolaou smear test is to detect the precancerous cervix lesions before they become invasive cancer. The frequency of the Pap smear test for which the females undergo depends upon age, poor socioeconomic status and the previous Pap smear findings.