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Soluble receptors and other substances that regulate proinflammatorycytokines in young and aging humans
2000
The journals of gerontology. Series A, Biological sciences and medical sciences
Relatively little is known about changes in soluble receptors and other agonists/antagonists that may regulate cytokine actions in aging humans. We have studied age-associated changes in human subjects of (a) the plasma levels of interleukin-1 soluble receptor (IL-lsRll), interleukin-1 receptor antagonist (IL-lra), tumor necrosis factor soluble receptor-II (75kDa; TNFsRH), and interleukin-6 soluble receptor (IL-6sR) and (b) the ability of their blood mononuclear cells to produce those soluble
doi:10.1093/gerona/55.1.b20
pmid:10719759
fatcat:6qnszdwmgza5zjo2yqctuvfhm4