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Kabachnik-Filds Reactions with 2,3-Trimethylene-1,2,3,4-Tetrahydropyrido[2,3-D]Pyrimidin-4-One
2020
International Journal of Mechanical and Production Engineering Research and Development
In the article synthesized 2,3-trimethylene-3,4-dihydropyrido[2,3-d]pyrimidin-4-one from 2-Aminonicotinic acid and pyrrolidone-2 in the presence different agents, such as PCl 5 , POCl 3 . Its reduction reaction with NaBH 4 carrying out. Obtained 2,3-trimethylene-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-4-one -this three-component coupling of a carbonyl, an amine and a hydrophosphoryl compoud leads to α-aminophosphonates, phosphorous acid-formaldehyde; aldehydes in three component system;
doi:10.24247/ijmperdjun20201150
fatcat:6fnex57mwbf77grae5xxbuaqse