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GSTM3 Function and Polymorphism in Cancer: Emerging but Promising
2020
Cancer Management and Research
Cancer is a major cause of human mortality; however, the molecular mechanisms and proteomic biomarkers that cause tumor progression in malignant tumors are either unknown or only partially revealed. Glutathione S-transferases mu3 (GSTM3), which belongs to a family of xenobiotic detoxifying phase II enzymes, is associated with carcinogen detoxification and the metabolism of exogenous electrophilic substances. It has been reported that GSTM3 has different polymorphisms in various tumor cells and
doi:10.2147/cmar.s272467
pmid:33116892
pmcid:PMC7585806
fatcat:sxvscsowsba77ag6u6vx6znqmu