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Cognitive Reserve and Brain Reserve in Prodromal Huntington's Disease
2013
Journal of the International Neuropsychological Society
Background-Huntington disease (HD) is associated with decline in cognition and progressive morphological changes in brain structures. Cognitive reserve may represent a mechanism by which disease-related decline may be delayed or slowed. The current study examined the relationship between cognitive reserve and longitudinal change in cognitive functioning and brain volumes among prodromal (gene expansion-positive) HD individuals. Methods-Participants were genetically-confirmed individuals with
doi:10.1017/s1355617713000507
pmid:23702309
pmcid:PMC3720793
fatcat:ssuaaswc4neevddksolj5b2r6q