Tannic acid: A Green Catalyst for the Eco-friendly Synthesis of 2,3-dihydroquinazolin-4(1H)-ones under Solvent Free Conditions

Mahdim Narouei, Nourallah Hazeri, Ebrahim Molashahi, Sara Zhaleh, Maryam Fatahpour
2017 Karaj branch Journal of Applied Chemical Research   unpublished
A new, facile, cost effective, and eco-friendly protocol is reported for the synthesis of 2,3-dihydroquinazoline-4-(1H)-ones exploring tannic acid as a novel, inexpensive, and biodegradable catalyst. A variety of dihydroquinazolins were prepared from aromatic aldehydes and anthranilamide using catalytic amount of tannic acid under solvent free conditions. Operational simplicity, high yield, and high atom-economy are the important features of this protocol.