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Translational research in hepatic encephalopathy: New diagnostic possibilities and new therapeutic approaches
2014
European Journal of Molecular and Clinical Medicine
Chronic liver disease (e.g. cirrhosis) affects brain function. There is a high incidence of mild cognitive impairment and psychomotor slowing in patients with cirrhosis. This condition, known as minimal hepatic encephalopathy (MHE) affects more than 2 million people in the European Union and has serious health, social and economic consequences. There are no effective treatments for MHE. Rat models of MHE reproduce cognitive and motor alterations seen in patients, showing reduced performance in
doi:10.1016/j.nhtm.2014.11.057
fatcat:uz2bq3545reezpynbvefp565ru