Experimental design, validation and computational modeling uncover DNA damage sensing by DNA-PK and ATM

R. J. Flassig, G. Maubach, C. Täger, K. Sundmacher, M. Naumann
2014 Molecular Biosystems  
A computational model predicts biphasic activation of γH2AX by DNA-PKcs and ATM-P upon DNA damage, which is induced by ionizing irradiation (IR).
doi:10.1039/c4mb00093e pmid:24833308 fatcat:jnf4pgxnpjcdfpzpi2jdb5oj2u