Comparative Histopathology of Biomphalaria glabrata, B. tenagophila and B. straminea with Variable Degrees of Resistance to Schistosoma mansoni Miracidia

Cecilia Pereira de Souza, Claudia Cunha Borges, Andréa Guimarães Santana, Zilton A Andrade
1997 Memórias do Instituto Oswaldo Cruz  
A comparative histopathological study of three snails species -Biomphalaria glabrata, B. tenagophila and B. straminea -which had been infected with Schistosoma mansoni miracidia revealed similar qualitative features, consisting of areas of sporocyst proliferation and differentiation associated with reactive host reaction, at the time they were actively eliminating great number of cercariae. However, in specimens that were exposed to miracidia but failed to eliminate cercariae later on,
more » ... histopathological pictures were observed in different snail species. While B. glabrata exhibited frequent focal (granulomatous) proliferation of amebocytes in several organs, B. tenagophila and B. straminea only rarely showed such reactive changes, suggesting that the mechanism of resistance to miracidial infection probably follows different pathways in the snail species studied.
doi:10.1590/s0074-02761997000400014 pmid:9361747 fatcat:iwbqnqyxdrgljmdqjrgku4pmea